Article
Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor.
The EMBO journal - 17 Jun 1996
Paushkin S V, Kushnirov V V, Smirnov V N, Ter-Avanesyan M D
Abstract excerpt
The Sup35p protein of yeast Saccharomyces cerevisiae is a homologue of the polypeptide chain release factor 3 (eRF3) of higher eukaryotes. It has been suggested that this protein may adopt a specific self-propagating conformation, similar to mammalian prions, giving rise to the [psi+] nonsense su...
Topics
- Alleles
- Base Sequence
- Biopolymers
- Endopeptidases
- Fungal Proteins
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Peptide Termination Factors
- Prions
- Protein Binding
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins