Article
MRP subfamily transporters and resistance to anticancer agents.
Journal of bioenergetics and biomembranes - 1 Dec 2001
Kruh G D, Zeng H, Rea P A, Liu G, Chen Z S, Lee K, Belinsky M G
Abstract excerpt
The MRP subfamily of ABC transporters from mammals consists of at least seven members, six of which have been implicated in the transport of amphipathic anions. MRP1, MRP2, and MRP3 bear a close structural resemblance, confer resistance to a variety of natural products as well as methotrexate, an...
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