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Article

Multidrug resistance associated proteins as determining factors of pharmacokinetics and pharmacodynamics of drugs.

Current drug metabolism - 1 Dec 2007

Yu Xue-Qing, Xue Charlie Changli, Wang Guangji, Zhou Shu-Feng

Abstract excerpt

The multidrug resistance associated proteins (MRP1, MRP2, MRP3, MRP4, MRP5, MRP6, MRP7, MRP8 and MRP9) belong to the ATP-binding cassette superfamily (ABCC family) of transporters. They are expressed differentially in the liver, kidney, intestine, brain and other tissues. These transporters are localized to the apical and/or basolateral membrane of the hepatocytes, enterocytes, renal proximal tubule cells and...

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Source

Identifiers

PMID: 18220559
DOI: 10.2174/138920007782798171

Genes

ABCC11
DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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