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Article

Should we consider gene x environment interaction in the hunt for quantitative trait loci?

Genetic epidemiology - 1 Jan 2001

Gauderman W J, Morrison J L, Siegmund K D

Abstract excerpt

We address the question of whether one can obtain increased power for finding a quantitative trait locus (QTL) if a gene x environment (G x E) interaction is incorporated directly into the linkage analysis. We consider both parametric and nonparametric analysis approaches to including G x E interaction. For the former, we utilize joint segregation and linkage analysis to estimate simultaneously the recombination...

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Identifiers

PMID: 11793788
DOI: 10.1002/gepi.2001.21.s1.s831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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