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Article

Association and linkage for age at onset of a common oligogenic disease using genetic variance component models.

Genetic epidemiology - 1 Jan 2001

Scurrah K J, Sheehan N A, Burton P R

Abstract excerpt

The aims of our analysis were: (1) to investigate association of single nucleotide polymorphisms (SNPs) and other covariates with age at onset in the simulated Genetic Analysis Workshop (GAW) 12 general population data, and (2) to use the polygenic random effects estimated during model fitting (sigma squared A random effects) as input to a Haseman-Elston linkage analysis. The association analyses used genetic...

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Identifiers

PMID: 11793761
DOI: 10.1002/gepi.2001.21.s1.s680

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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