Article
Genome-wide linkage analysis using genetic variance components of alcohol dependency-associated censored and continuous traits.
Genetic epidemiology - 1 Jan 1999
Palmer L J, Tiller K J, Burton P R
Abstract excerpt
We used variance-components analysis to investigate the additive genetic effects regulating some of the phenotypes included in the GAW11 data set. Variance-components models were fitted using Gibbs sampling methods in BUGS v 0.6. Linkage analyses for both multivariate normal (MvN) traits and right censored survival times (age-of-onset) were based upon standard Haseman-Elston identity-by-descent sib-pair methods...
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