Article
Predicting quantitative trait levels by modeling SNP interaction.
Genetic epidemiology - 1 Jan 2001
Fijal B A, Kim L L, Buxbaum S G, Witte J S
Abstract excerpt
Predicting phenotype from genotype is difficult when the phenotype is affected by a gene with numerous weakly penetrant alleles that differ only in the pattern of their single nucleotide polymorphisms (SNPs). While it is probable that SNP interactions affect phenotype, to our knowledge no one has determined the most effective way of evaluating whether SNPs interact and of modeling the interaction. Therefore, to...
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