Article
SNPing away at candidate genes.
Genetic epidemiology - 1 Jan 2001
Suchard M A, Bailey J N, Elashoff D A, Sinsheimer J S
Abstract excerpt
We develop regression methodology to identify subsets of single nucleotide polymorphisms (SNPs) within candidate genes related to quantitative traits and apply our methods to the simulated Genetic Analysis Workshop (GAW) 12 data set. In the data set we find 694 SNP loci with minimum allele frequencies of at least 0.01. We assume an additive casual model between these SNPs and all five quantitative traits. After...
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