Article
Multipoint linkage analysis under heterogeneity: incorporation of parametric and nonparametric approaches.
Genetic epidemiology - 1 Jan 2001
Chiu Y F, Addington A M, Beaty T H, Klein A P, Liang K Y
Abstract excerpt
Using a recently developed multipoint parametric method, which tests for linkage in the presence of heterogeneity, we performed a genome-wide search for linkage using the German asthma data. Both dominant and recessive models were assumed in this parametric approach. Identity-by-descent (IBD) sha...
Topics
- Adult
- Alleles
- Asthma
- Child
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 6
- Chromosomes, Human, Pair 9
- Female
- Genetic Heterogeneity
- Genetic Predisposition to Disease
- Genetics, Population
- Genome
- Germany
- Humans
- Male
- Models, Genetic
- United States