Article
A simple method to localise pleiotropic susceptibility loci using univariate linkage analyses of correlated traits.
European journal of human genetics : EJHG - 1 Aug 2006
Ferreira Manuel A R, Visscher Peter M, Martin Nicholas G, Duffy David L
Abstract excerpt
Univariate linkage analysis is used routinely to localise genes for human complex traits. Often, many traits are analysed but the significance of linkage for each trait is not corrected for multiple trait testing, which increases the experiment-wise type-I error rate. In addition, univariate anal...
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