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Article

Protein determinants of RNA binding by DNA polymerase of the T4-related bacteriophage RB69.

The Journal of biological chemistry - 6 Sept 2002

Petrov Vasiliy M, Ng San-San, Karam Jim D

Abstract excerpt

DNA polymerase (gp43) of phage T4 plays two biological roles, one as an essential DNA binding replication enzyme and the other as an mRNA-specific autogenous translational repressor. Binding of T4 gp43 to its mRNA target (translational operator RNA) interferes with gp43-DNA interactions, but it is unclear how the protein determinants for binding DNA are affected by the dynamics of gp43-mRNA interactions. We have...

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PMID: 12087102
DOI: 10.1074/jbc.M204754200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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