Article
Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development.
Developmental biology - 15 Oct 2001
Zent R, Bush K T, Pohl M L, Quaranta V, Koshikawa N, Wang Z, Kreidberg J A, Sakurai H, Stuart R O, Nigám S K
Abstract excerpt
Branching morphogenesis of the ureteric bud (UB) [induced by the metanephric mesenchyme (MM)] is necessary for normal kidney development. The role of integrins in this complex developmental process is not well understood. However, the recent advent of in vitro model systems to study branching of UB cells and isolated UB tissue makes possible a more detailed analysis of the integrins involved. We detected integrin...
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