Article
Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.
Developmental biology - 1 Aug 2007
Rebustini Ivan T, Patel Vaishali N, Stewart Julian S, Layvey Ann, Georges-Labouesse Elisabeth, Miner Jeffrey H, Hoffman Matthew P
Abstract excerpt
Laminin alpha chains have unique spatiotemporal expression patterns during development and defining their function is necessary to understand the regulation of epithelial morphogenesis. We investigated the function of laminin alpha5 in mouse submandibular glands (SMGs). Lama5(-/-) SMGs have a str...
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