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Integrins in kidney development, function, and disease

1 Aug 2000

Abstract excerpt

Integrins are heterodimeric cell surface receptors that mediate heterophilic cell-cell interactions and interactions between cells and the extracellular matrix (Hynes RO. Cell 69: 11-25, 1991). As such, they are involved in morphogenetic processes during development, as well as in the maintenance of normal tissue architecture in fully developed organs. Integrins are now recognized to be a large family of...

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PMID: 10919841
DOI: 10.1152/ajprenal.2000.279.2.f233

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