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Article

Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation.

The Journal of cell biology - 24 Jun 2002

Li Shaohua, Harrison David, Carbonetto Salvatore, Fassler Reinhard, Smyth Neil, Edgar David, Yurchenco Peter D

Abstract excerpt

Laminin-1 is essential for early embryonic basement membrane assembly and differentiation. Several steps can be distinguished, i.e., the expression of laminin and companion matrix components, their accumulation on the cell surface and assembly into basement membrane between endoderm and inner cell mass, and the ensuing differentiation of epiblast. In this study, we used differentiating embryoid bodies derived...

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Identifiers

PMID: 12082085
DOI: 10.1083/jcb.200203073
PMCID: PMC2173546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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