Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Crosstalk between Myc and activating transcription factor 2 (ATF2): Myc prolongs the half-life and induces phosphorylation of ATF2.

Oncogene - 6 Dec 2001

Miethe J, Schwartz C, Wottrich K, Wenning D, Klempnauer K H

Abstract excerpt

Myc is a key regulator of cell growth, differentiation and apoptosis, and affects cell fate decisions by activating as well as by inhibiting the expression of cellular genes. Myc is a member of the basic region-helix-loop-helix-leucine zipper (b-HLH-Zip) class of transcription factors, which heterodimerizes with the Max protein and recognizes a consensus Myc binding motif. Stimulation of gene expression by Myc is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Activating Transcription Factor 2
Share to Cell Line, Transformed

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclic AMP Response Element-Binding Protein

Share to Fungal Proteins

Share to Genes, Reporter

Share to Half-Life

Share to Recombinant Fusion Proteins

Share to Transcriptional Activation

Source

Identifiers

PMID: 11781825
DOI: 10.1038/sj.onc.1204966

Genes

ATF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Crosstalk between Myc and activating transcription factor 2 (ATF2): Myc prolongs the half-life and induces phosphorylation of ATF2.PMID 11781825Read ↗

Molecular Crosstalk Between MYC and HIF in CancerSemantic proximity Read ↗

Viral mutations enhance the Max binding properties of the vMyc b-HLH-LZ domain.Semantic proximity Read ↗

MYC Analysis in Cancer and Evolution.Semantic proximity Read ↗

Transcriptional activation by the Myc oncoprotein.Semantic proximity Read ↗

Genomic and Proteomic Analysis Reveals a Threshold Level of MYC Required for Tumor MaintenanceSemantic proximity Read ↗

Myc and Max proteins possess distinct transcriptional activities.Semantic proximity Read ↗

Functional analysis of the carboxy-terminal transforming region of v-Myc: binding to Max is necessary, but not sufficient, for cellular transformation.Semantic proximity Read ↗

Ubiquitination and degradation of ATF2 are dimerization dependent.Semantic proximity Read ↗

Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif.Semantic proximity Read ↗

Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization.Semantic proximity Read ↗

Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.Semantic proximity Read ↗

Function of the c-Myc Oncogenic Transcription FactorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.