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Article

Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif.

Oncogene - 7 Jul 2016

Thomas L R, Foshage A M, Weissmiller A M, Popay T M, Grieb B C, Qualls S J, Ng V, Carboneau B, Lorey S, Eischen C M, Tansey W P

Abstract excerpt

The MYC family of oncogenes encodes a set of three related transcription factors that are overexpressed in many human tumors and contribute to the cancer-related deaths of more than 70,000 Americans every year. MYC proteins drive tumorigenesis by interacting with co-factors that enable them to regulate the expression of thousands of genes linked to cell growth, proliferation, metabolism and genome stability. One...

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Share to Amino Acid Motifs
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26522729
DOI: 10.1038/onc.2015.416
PMCID: PMC4853269

Genes

MYC
HBM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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