Article
Myc and Max proteins possess distinct transcriptional activities.
Nature - 1 Oct 1992
Kretzner L, Blackwood E M, Eisenman R N
Abstract excerpt
The Myc family proteins are thought to be involved in transcription because they have both a carboxy-terminal basic-helix-loop-helix-zipper (bHLH-Z) domain, common to a large class of transcription factors, and an amino-terminal fragment which, for c-Myc, has transactivating function when assayed in chimaeric constructs. In addition, c-, N- and L-Myc proteins heterodimerize, in vitro and in vivo, with the bHLH-Z...
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