Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TNF and LTA gene polymorphisms reveal different risk in gastric and duodenal ulcer patients.

Genes and immunity - 1 Dec 2001

Lanas A, García-González M A, Santolaria S, Crusius J B, Serrano M T, Benito R, Peña A S

Abstract excerpt

A small proportion of patients infected with Helicobacter pylori or using non-steroidal anti-inflammatory drugs (NSAIDs) develops peptic ulcer disease. Since family studies have shown the importance of the genetic background of the host in the development of gastric and duodenal ulcers, immunogenetic factors involved in the regulation of inflammation deserve further study. Polymorphisms in the genes encoding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Demography
Share to Duodenal Ulcer
Share to Helicobacter Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Helicobacter pylori

Share to Lymphotoxin-alpha

Share to Peptide Fragments

Share to Stomach Ulcer

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 11781708
DOI: 10.1038/sj.gene.6363798

Genes

TNF
LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TNF and LTA gene polymorphisms reveal different risk in gastric and duodenal ulcer patients.PMID 11781708Read ↗

Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer.Semantic proximity Read ↗

No allelic variant associations of the IL-1 and TNF gene polymorphisms in the susceptibility to duodenal ulcer disease.Semantic proximity Read ↗

TNF gene polymorphisms and Helicobacter Pylori infection in gastric carcinogenesis in Chinese population.Semantic proximity Read ↗

Assessment of TNFA polymorphisms at positions -857 and -863 in Polish peptic ulcer patients.Semantic proximity Read ↗

Association between TNFA Gene Polymorphisms and Helicobacter pylori Infection: A Meta-Analysis.Semantic proximity Read ↗

TNF/LTA polymorphisms and risk for gastric cancer/duodenal ulcer in the Korean population.Semantic proximity Read ↗

Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer.Semantic proximity Read ↗

Investigation of -308G>A and -1031T>C polymorphisms in the TNFA promoter region in Polish peptic ulcer patients.Semantic proximity Read ↗

A candidate gene approach of immune mediators effecting the susceptibility to and severity of upper gastrointestinal tract diseases in relation to Helicobacter pylori and Epstein-Barr virus infections.Semantic proximity Read ↗

Association of specific haplotype of TNFalpha with Helicobacter pylori-mediated duodenal ulcer in eastern Indian population.Semantic proximity Read ↗

The polymorphic IL-1B and IL-1RN genes in the aetiopathogenesis of peptic ulcer.Semantic proximity Read ↗

Association of CYP2C19, TNF-α, NOD1, NOD2, and PPARγ polymorphisms with peptic ulcer disease enhanced by Helicobacter pylori infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.