Article
TNF gene polymorphisms and Helicobacter Pylori infection in gastric carcinogenesis in Chinese population.
The American journal of gastroenterology - 1 Feb 2005
Li Chun, Xia Bing, Yang Yi, Li Jin, Xia Harry Hua-Xiang
Abstract excerpt
BACKGROUND AND AIMS: Helicobacter pylori (H. pylori) is a major cause of chronic gastritis and peptic ulcer disease, and a definite carcinogen for gastric adenocarcinoma. However, the underlying pathogenic mechanisms have not been fully understood although the interactions between environmental, bacterial, and multiple genetic components are likely to be involved. Tumor necrosis factor (TNF) is a key cytokine...
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