Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer.

World journal of gastroenterology - 14 Mar 2010

Sugimoto Mitsushige, Yamaoka Yoshio, Furuta Takahisa

Abstract excerpt

Pro-inflammatory cytokines are produced in the gastric mucosa by inflammatory cells activated by chronic Helicobacter pylori (H. pylori) infection. Polymorphisms of these cytokine genes are associated with individual differences in gastric mucosal cytokine mRNA level, which result in differences in gastric mucosal inflammation, acid inhibition and gastroduodenal disease risk in response to H. pylori infection....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to TNF gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Helicobacter pylori-related gastroenterology studies

Share to Interleukins

Share to Peptic Ulcer

Share to Polymorphism, Genetic

Share to Stomach Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 20222161
DOI: 10.3748/wjg.v16.i10.1188
PMCID: PMC2839170

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer.PMID 20222161Read ↗

Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer.Semantic proximity Read ↗

Effects of interleukin-10 gene polymorphism on the development of gastric cancer and peptic ulcer in Japanese subjects.Semantic proximity Read ↗

Novel interleukin-4 and interleukin-1 receptor antagonist gene variations associated with non-cardia gastric cancer in Japan: comprehensive analysis of 207 polymorphisms of 11 cytokine genes.Semantic proximity Read ↗

Cytokine gene polymorphisms and the risk of adenocarcinoma of the stomach in the European prospective investigation into cancer and nutrition (EPIC-EURGAST).Semantic proximity Read ↗

The role of interleukin DNA polymorphisms in gastric cancer.Semantic proximity Read ↗

Pro- and anti-inflammatory cytokines gene polymorphisms and Helicobacter pylori infection: interactions influence outcome.Semantic proximity Read ↗

A candidate gene approach of immune mediators effecting the susceptibility to and severity of upper gastrointestinal tract diseases in relation to Helicobacter pylori and Epstein-Barr virus infections.Semantic proximity Read ↗

The effects of genetic polymorphisms of IL-6, IL-8, and IL-10 on Helicobacter pylori-induced gastroduodenal diseases in Korea.Semantic proximity Read ↗

Association of genetic polymorphisms of interleukins with gastric cancer and precancerous gastric lesions in a high-risk Chinese population.Semantic proximity Read ↗

Profiles of gene polymorphisms in cytokines and Toll-like receptors with higher risk for gastric cancer.Semantic proximity Read ↗

The effects of genetic polymorphisms of IL-1 and TNF-A on Helicobacter pylori-induced gastroduodenal diseases in Korea.Semantic proximity Read ↗

Associations between cytokine gene polymorphisms and susceptibility to Helicobacter pylori infection and Helicobacter pylori related gastric cancer, peptic ulcer disease: A meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.