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Article

Association of CYP2C19, TNF-α, NOD1, NOD2, and PPARγ polymorphisms with peptic ulcer disease enhanced by Helicobacter pylori infection.

Saudi medical journal - 1 Jan 2021

Al-Eitan Laith N, Almomani Fouad A, Al-Khatib Sohaib M

Abstract excerpt

OBJECTIVES: To assess the correlation between a number of genetic variations of CYP2C19, TNF-α, NOD1, NOD2, and PPARγ genes with the severity of Helicobacter pylori (H. pylori) infections and peptic ulcers (PU). METHODS: A retrospective cross-sectional design was used in this study. Formalin-fixed paraffin-embedded (FFPE) tissue was used to extract genomic DNA that was collected from Jordanian patients who...

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Identifiers

PMID: 33399167
DOI: 10.15537/smj.2021.1.25654
PMCID: PMC7989310

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