Article
TNF/LTA polymorphisms and risk for gastric cancer/duodenal ulcer in the Korean population.
Cytokine - 21 Oct 2004
Lee Seong-Gene, Kim Byungsik, Yook Jung-Hwan, Oh Sung-Tae, Lee Inchul, Song Kyuyoung
Abstract excerpt
The tumor necrosis factor-alpha (TNF) and lymphotoxin-alpha (LTA) are proinflammatory cytokines with immunoregulatory effects. TNF is also known to inhibit gastric acid secretion. Previously we have shown that the known proinflammatory genotypes, IL-1B -31C/+ and IL-1RN *2/*2, were not associated with increased risks for gastric cancer/duodenal ulcer in the Korean population. In this study, we tested the...
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