Article
DNA sequence variability of IGHG3 alleles associated to the main G3m haplotypes in human populations.
European journal of human genetics : EJHG - 1 Oct 2001
Dard P, Lefranc M P, Osipova L, Sanchez-Mazas A
Abstract excerpt
The present study investigates the molecular basis of the G3m polymorphism expressed by the heavy constant domains of human immunoglobulins gamma 3 chains. By using a new protocol allowing the specific cloning of IGHG3 genes, a total of 51 full-length IGHG3 genomic sequences (about 2 kb) isolated from African, Siberian, West Asian and European population samples were sequenced. IGHG3 sequences were assigned...
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