Article
BamHI-SacI RFLP and Gm analysis of the immunoglobulin IGHG genes in the Northern Selkups (west Siberia): new haplotypes with deletion, duplication and triplication.
Human genetics - 1 Dec 1999
Osipova L P, Posukh O L, Wiebe V P, Miyazaki T, Matsumoto H, Lefranc G, Lefranc M P
Abstract excerpt
Gm immunoglobulin allotypes have been studied in 1157 individuals of seven Northern Selkup populations, which account for 80% of the entire population of this west Siberian tribe. This study confirms that the northern Selkup populations are a Caucasoid-Mongoloid hybrid. Restriction fragment length polymorphism (RFLP) analysis of the IGHG genes using double BamHI-SacI digests, performed on 475 DNA samples, allowed...
Topics
- Arctic Regions
- Asian People
- Blotting, Southern
- Female
- Gene Deletion
- Gene Duplication
- Genes, Immunoglobulin
- Genetics, Population
- Genotype
- Haplotypes
- Humans