Article
Polymorphism of the IGHG3 gene in cattle.
Immunogenetics - 1 Jan 1997
Rabbani H, Brown W R, Butler J E, Hammarström L
Abstract excerpt
We cloned and analyzed the gene (IGHG3) encoding cattle IgG3 using a spleen cDNA library and a genomic phage clone. IGHG3 differs most remarkably from IGHG1 and IGHG2 in the structure of its hinge. The IGHG3 hinge is encoded by two exons, one of which encodes a 22 amino acid 3' extension of the C...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Cattle
- Chromosome Mapping
- Cloning, Molecular
- DNA Primers
- Electrophoresis, Gel, Pulsed-Field
- Genomic Library
- Immunoglobulin G
- Immunoglobulin Heavy Chains
- Molecular Sequence Data
- Polymorphism, Restriction Fragment Length
