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Article

Gene segments encoding membrane domains of the human immunoglobulin gamma 3 and alpha chains.

Immunogenetics - 1 Jan 1990

Bensmana M, Lefranc M P

Abstract excerpt

The carboxyterminal region of the heavy chains, according to its hydrophilic or hydrophobic properties, determines whether the immunoglobulin will be secreted or membrane-bound. We have determined the nucleotide sequences of the human IGHG3, IGHA1, and IGHA2 membrane exons isolated from genomic DNA libraries. The IGHG3 M1 and M2 exons are separated by a long intron of 2.1 kilobases (kb) containing an highly...

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Identifiers

PMID: 1979064
DOI: 10.1007/BF00211646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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