Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic refinement and physical mapping of a chromosome 16q candidate region for inflammatory bowel disease.

European journal of human genetics : EJHG - 1 Oct 2001

Zouali H, Chamaillard M, Lesage S, Cézard J P, Colombel J F, Belaiche J, Almer S, Tysk C, Montague S, Gassull M, Christensen S, Finkel Y, Gower-Rousseau C, Modigliani R, Macry J, Selinger-Leneman H, Thomas G, Hugot J P

Abstract excerpt

Crohn's disease (CD) is a complex genetic disorder for which a susceptibility gene, IBD1, has been mapped within the pericentromeric region of chromosome 16. In order to refine the location of IBD1, 77 multiplex CD families were genotyped for 26 microsatellite markers evenly spaced by approximately 1 cM. Nonparametric linkage analyses exhibited a maximum NPL score of 3.49 (P=2.37x10(-4)) in a region centred by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Southern
Share to Chromosomes, Artificial, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 16

Share to Contig Mapping

Share to Crohn Disease

Share to Expressed Sequence Tags

Share to In Situ Hybridization, Fluorescence

Share to Sequence Tagged Sites

Source

Identifiers

PMID: 11781683
DOI: 10.1038/sj.ejhg.5200710

Genes

NPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic refinement and physical mapping of a chromosome 16q candidate region for inflammatory bowel disease.PMID 11781683Read ↗

Mapping of a susceptibility locus for Crohn's disease on chromosome 16.Semantic proximity Read ↗

Mutation detection and physical mapping of the CD11 gene cluster in association with inflammatory bowel disease.Semantic proximity Read ↗

Genetic analysis in Italian families with inflammatory bowel disease supports linkage to the IBD1 locus--a GISC study.Semantic proximity Read ↗

Inflammatory bowel disease gene hunting by linkage analysis: rationale, methodology, and present status of the field.Semantic proximity Read ↗

Not one but two inflammatory bowel disease susceptibility loci map to chromosome 16.Semantic proximity Read ↗

Association of susceptibility locus for inflammatory bowel disease on chromosome 16 with both ulcerative colitis and Crohn's disease.Semantic proximity Read ↗

Progress towards identifying inflammatory bowel disease susceptibility genes.Semantic proximity Read ↗

Analysis of Australian Crohn's disease pedigrees refines the localization for susceptibility to inflammatory bowel disease on chromosome 16.Semantic proximity Read ↗

Genetic variation at the chromosome 16 chemokine gene cluster: development of a strategy for association studies in complex disease.Semantic proximity Read ↗

International collaboration provides convincing linkage replication in complex disease through analysis of a large pooled data set: Crohn disease and chromosome 16.Semantic proximity Read ↗

Genetic analysis of inflammatory bowel disease in a large European cohort supports linkage to chromosomes 12 and 16.Semantic proximity Read ↗

Evidence for a NOD2-independent susceptibility locus for inflammatory bowel disease on chromosome 16p.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.