Article
Mapping of a susceptibility locus for Crohn's disease on chromosome 16.
Nature - 29 Feb 1996
Hugot J P, Laurent-Puig P, Gower-Rousseau C, Olson J M, Lee J C, Beaugerie L, Naom I, Dupas J L, Van Gossum A, Orholm M, Bonaiti-Pellie C, Weissenbach J, Mathew C G, Lennard-Jones J E, Cortot A, Colombel J F, Thomas G
Abstract excerpt
Crohn's disease (CD) and ulcerative colitis are the major forms of chronic inflammatory bowel diseases in the western world, and occur in young adults with an estimated prevalence of more than one per thousand inhabitants. The causes of inflammatory bowel diseases remain unknown, but genetic epidemiology studies suggest that inherited factors may contribute in part to variation in individual susceptibility to...
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