Article
Analysis of Australian Crohn's disease pedigrees refines the localization for susceptibility to inflammatory bowel disease on chromosome 16.
Annals of human genetics - 1 Jul 1998
Cavanaugh J A, Callen D F, Wilson S R, Stanford P M, Sraml M E, Gorska M, Crawford J, Whitmore S A, Shlegel C, Foote S, Kohonen-Corish M, Pavli P
Abstract excerpt
A number of localizations for the putative susceptibility gene(s) have been identified for both Crohn's disease and ulcerative colitis. In a genome wide scan, Hugot et al. (1996) identified a region on chromosome 16 which appeared to be responsible for the inheritance of inflammatory bowel disease in a small proportion of families. Subsequent work has suggested that this localization is important for...
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