Article
Genetic analysis in Italian families with inflammatory bowel disease supports linkage to the IBD1 locus--a GISC study.
European journal of human genetics : EJHG - 1 Jul 1999
Annese V, Latiano A, Bovio P, Forabosco P, Piepoli A, Lombardi G, Andreoli A, Astegiano M, Gionchetti P, Riegler G, Sturniolo G C, Clementi M, Rappaport E, Fortina P, Devoto M, Gasparini P, Andriulli A
Abstract excerpt
Epidemiological studies suggest that inherited factors influence susceptibility to inflammatory bowel disease (IBD), and some candidate loci have been described. In order to verify whether the same loci are responsible for predisposition to IBD in our population, we carried out a linkage study in a series of 58 Italian families with Crohn's disease (CD) and ulcerative colitis (UC). HLA-DQ alleles, motilin gene,...
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