Article
Mutation detection and physical mapping of the CD11 gene cluster in association with inflammatory bowel disease.
Immunogenetics - 1 Feb 2002
Frenzel Henning, Hampe Jochen, Huse Klaus, Mascheretti Silvia M, Croucher Peter P, Lynch Nicholas J, Siebert Reiner, Platzer Matthias, Schreiber Stefan
Abstract excerpt
A genetic component in the etiology of inflammatory bowel disease (IBD) has clearly been demonstrated by epidemiological and genetic linkage studies. Linkage to IBD on proximal Chromosome (Chr) 16p is well established and replicated. A stratification experiment showed that the recent identification of a disease gene on the q arm does not interfere with the approach on the p arm, and the linkage peak is still...
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