Article
Genetic analysis of inflammatory bowel disease in a large European cohort supports linkage to chromosomes 12 and 16.
Gastroenterology - 1 Nov 1998
Curran M E, Lau K F, Hampe J, Schreiber S, Bridger S, Macpherson A J, Cardon L R, Sakul H, Harris T J, Stokkers P, Van Deventer S J, Mirza M, Raedler A, Kruis W, Meckler U, Theuer D, Herrmann T, Gionchetti P, Lee J, Mathew C, Lennard-Jones J
Abstract excerpt
BACKGROUND & AIMS: Inflammatory bowel disease (IBD) is a complex disorder of unknown etiology. Epidemiological investigations suggest a genetic basis for IBD. Recent genetic studies have identified several IBD linkages. The significance of these linkages will be determined by studies in large patient collections. The aim of this study was to replicate IBD linkages on chromosomes 12 and 16 in a large European...
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