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Article

Combined COMT and GST genotypes and hormone replacement therapy associated breast cancer risk.

Pharmacogenetics - 1 Jan 2002

Mitrunen Katja, Kataja Vesa, Eskelinen Matti, Kosma Veli-Matti, Kang Daehee, Benhamou Simone, Vainio Harri, Uusitupa Matti, Hirvonen Ari

Abstract excerpt

Our previous studies suggested that both COMT and GST genotypes might modify individual breast cancer risk. Here, we extended the studies to examine the potential combined effect of these genotypes in susceptibility to breast cancer. Our study population consisted of 483 Finnish breast cancer cases and 482 population control subjects. The odds ratios (ORs) and (95%) confidence intervals (CIs) were calculated by...

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Source

Identifiers

PMID: 11773866
DOI: 10.1097/00008571-200201000-00009

Genes

COMT
GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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