Article
Combined effect of GSTM1, GSTT1, and COMT genotypes in individual breast cancer risk.
Breast cancer research and treatment - 1 Nov 2004
Park Sue Kyung, Yim Dong-Seok, Yoon Kyung-Sik, Choi In-Mi, Choi Ji-Yeob, Yoo Keun-Young, Noh Dong-Young, Choe Kuk-Jin, Ahn Sei-Hyun, Hirvonen Ari, Kang Daehee
Abstract excerpt
Our previous studies suggested that both catechol O-methyl transferase (COMT) and glutathione S-transferase (GST) M1 and T1 genotypes are associated with breast cancer risk. Here we extended the studies to evaluate the potential combined effect of these genotypes in individual breast cancer risk. Incident breast cancer cases (n = 202) and controls (n = 299) with no previous cancer were recruited from three...
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