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Article

Quantitative proteomic analysis of amastigotes from Leishmania (L.) amazonensis LV79 and PH8 strains reveals molecular traits associated with the virulence phenotype.

PLoS neglected tropical diseases - 1 Nov 2017

de Rezende Eloiza, Kawahara Rebeca, Peña Mauricio S, Palmisano Giuseppe, Stolf Beatriz S

Abstract excerpt

BACKGROUND: Leishmaniasis is an antropozoonosis caused by Leishmania parasites that affects around 12 million people in 98 different countries. The disease has different clinical forms, which depend mainly on the parasite genetics and on the immunologic status of the host. The promastigote form of the parasite is transmitted by an infected female phlebotomine sand fly, is internalized by phagocytic cells, mainly...

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PMID: 29176891
DOI: 10.1371/journal.pntd.0006090
PMCID: PMC5720813

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