Article
Interacting protein kinases involved in the regulation of flagellar length.
Molecular biology of the cell - 1 Apr 2006
Erdmann Maja, Scholz Anne, Melzer Inga M, Schmetz Christel, Wiese Martin
Abstract excerpt
A striking difference of the life stages of the protozoan parasite Leishmania is a long flagellum in the insect stage promastigotes and a rudimentary organelle in the mammalian amastigotes. LmxMKK, a mitogen-activated protein (MAP) kinase kinase from Leishmania mexicana, is required for growth of a full-length flagellum. We identified LmxMPK3, a MAP kinase homologue, with a similar expression pattern as LmxMKK...
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