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Repurposing approved protein kinase inhibitors as potent anti-leishmanials targeting Leishmania MAP kinases

2024-02-18

Abstract excerpt

Leishmaniasis is a vast array of chronic diseases caused by the protozoan parasite of the genus Leishmania transmitted by the sandfly belonging to the genus Phlebotomus (Old World) and Lutzomyia (New World). Among the various factors that contribute to the virulence and pathogenesis of the disease, protein kinases play crucial role in modulating the parasites biology in the host system. There are no specific drugs...

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Literature Corpus work
d5b409c0-2a9c-51de-acfa-455bbd487444
DOI
10.1101/2024.02.16.580710
Open publication

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Repurposing approved protein kinase inhibitors as potent anti-leishmanials targeting Leishmania MAP kinasesDOI 10.1101/2024.02.16.580710
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