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Article

Complex signatures of natural selection at the Duffy blood group locus.

American journal of human genetics - 1 Feb 2002

Hamblin Martha T, Thompson Emma E, Di Rienzo Anna

Abstract excerpt

The Duffy blood group locus (FY) has long been considered a likely target of natural selection, because of the extreme pattern of geographic differentiation of its three major alleles (FY*B, FY*A, and FY*O). In the present study, we resequenced the FY region in samples of Hausa from Cameroon (fixed for FY*O), Han Chinese (fixed for FY*A), Italians, and Pakistanis. Our goals were to characterize the signature of...

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Identifiers

PMID: 11753822
DOI: 10.1086/338628
PMCID: PMC419988

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