Adaptive admixture at <i>ACKR1</i> (the Duffy locus) may have shaped <i>Plasmodium vivax</i> prevalence in Oman

Abstract excerpt

Malaria in humans is largely caused by two divergent species of Plasmodium parasites, P. vivax and P. falciparum , both of which have driven the spread of protective alleles in human populations. Notably, an erythrocyte-specific Duffy null allele (Fy ES ) confers resistance to P. vivax malaria and has been identified as a target of strong, recent positive selection in multiple African admixed populations. Her...

Topics

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• Alleles
• Gene Frequency
• Genetics, Population
• Malaria, Vivax
• Plasmodium vivax
• Prevalence
• Receptors, Cell Surface
• Selection, Genetic

Identifiers and source

Literature Corpus work

a152c557-4b2b-544b-b2d4-ffeb10fffa1f

DOI

10.1101/2024.03.06.583766