Article
Natural selection mediated association of the Duffy (FY) gene polymorphisms with Plasmodium vivax malaria in India.
PloS one - 1 Jan 2012
Chittoria Anita, Mohanty Sujata, Jaiswal Yogesh Kumar, Das Aparup
Abstract excerpt
The Duffy (Fy) antigens act as receptors for chemokines as well as for Plasmodium vivax to invade human RBCs. A recent study has correlated the occurrence of the FY*A allele of Duffy gene with decreased susceptibility to vivax malaria, but no epidemiological correlation between the distribution of FY*A allele and incidences of vivax malaria has been established so far. Furthermore, if such correlations exist,...
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