Article
Identifying genes for male sex determination in humans.
The Journal of experimental zoology - 1 Nov 2001
Ostrer H
Abstract excerpt
The convergence of genetic and molecular technologies has led to the identification of a number of genes for male sex determination. The observation of chromosomal translocations, deletions, and duplications in sex reversed individuals was instrumental for the positional cloning of SRY, SOX9, WT1, and DAX1. Cloning by protein-DNA interaction was required for the identification of SF1. The observation of an...
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