Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mammalian sex determination: from gonads to brain.

Molecular genetics and metabolism - 1 Oct 1998

Vilain E, McCabe E R

Abstract excerpt

In mammals, sex is determined by the Y chromosome, which encodes a testis-determining factor (TDF). This factor causes the undifferentiated embryonic gonads to develop as testes rather than ovaries. The testes subsequently produce the male sex hormones that are responsible for all male sexual characteristics. In 1990, the sex-determining gene, TDF, was identified and termed SRY in humans (Sry in mice). It encodes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Brain
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Biological

Share to Molecular Sequence Data

Share to Mutation

Share to Nuclear Proteins

Source

Identifiers

PMID: 9787099
DOI: 10.1006/mgme.1998.2749

Genes

SRY
SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mammalian sex determination: from gonads to brain.PMID 9787099Read ↗

Vertebrate sex determination: many means to an endSemantic proximity Read ↗

SEX IN THE 90s:<i>SRY</i>and the Switch to the Male PathwaySemantic proximity Read ↗

Whatever happened to SRY?Semantic proximity Read ↗

Battle of the sexes: new insights into genetic pathways of gonadal development.Semantic proximity Read ↗

Sex determination in humans.Semantic proximity Read ↗

Mammalian sex determination—insights from humans and miceSemantic proximity Read ↗

Turning on the male--SRY, SOX9 and sex determination in mammals.Semantic proximity Read ↗

Gonadal sex determination in vertebrates: rethinking established mechanismsSemantic proximity Read ↗

Identifying genes for male sex determination in humans.Semantic proximity Read ↗

Regulation of Sexual Dimorphism in MammalsSemantic proximity Read ↗

Sex determination, gonadal sex differentiation, and plasticity in vertebrate speciesSemantic proximity Read ↗

The Molecular Action and Regulation of the Testis-Determining Factors, SRY (Sex-Determining Region on the Y Chromosome) and SOX9 [SRY-Related High-Mobility Group (HMG) Box 9]Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.