Article
Battle of the sexes: new insights into genetic pathways of gonadal development.
Transactions of the American Clinical and Climatological Association - 1 Jan 2003
Jameson J Larry, Achermann John C, Ozisik Gokhan, Meeks Joshua J
Abstract excerpt
Sex determination is governed by a series of genetic switches that influence cell fate and differentiation during critical periods of gonadal development. Remarkably, the primordial fetal gonad is bipotential. Therefore, gonadal development provides an excellent opportunity to identify genes involved in differential organogenesis. The identification of the testis-determining gene, SRY (Sex-reversed on the Y), was...
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