Article
Human male sex determination and sexual differentiation: pathways, molecular interactions and genetic disorders.
Medicina (Kaunas, Lithuania) - 1 Jan 2005
Kucinskas Laimutis, Just Walter
Abstract excerpt
The complex mechanisms are responsible for male sex determination and differentiation. The steps of formation of the testes are dependent on a series of Y-linked, X-linked and autosomal genes actions and interactions. After formation of testes the gonads secrete hormones, which are essential for the formation of the male genitalia. Hormones are transcription regulators, which function by specific receptors....
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