Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Uncommon TGFBRI allele is not associated with increased susceptibility to colon cancer.

Genes, chromosomes & cancer - 1 Dec 2001

Samowitz W S, Curtin K, Leppert M F, Slattery M L

Abstract excerpt

Previous studies have suggested that an allele of the transforming growth factor-beta type I receptor (TGFBRI) gene that codes for six instead of the usual nine alanines in a polyalanine repeat is associated with an increased susceptibility to colon cancer, and that the six-alanine homozygote is seen only in individuals with some form of cancer. We evaluated this TGFBRI polymorphism in a population-based sample...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colonic Neoplasms

Share to Genetic Predisposition to Disease

Share to Receptors, Transforming Growth Factor beta

Source

Identifiers

PMID: 11746979
DOI: 10.1002/gcc.1203

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Uncommon TGFBRI allele is not associated with increased susceptibility to colon cancer.PMID 11746979Read ↗

TbetaR-I(6A) is a candidate tumor susceptibility allele.Semantic proximity Read ↗

The TGFBR1*6A allele is not associated with susceptibility to colorectal cancer in a Spanish population: a case-control study.Semantic proximity Read ↗

Transforming growth factor beta receptor I polyalanine repeat polymorphism does not increase ovarian cancer risk.Semantic proximity Read ↗

Lack of an association between the TGFBR1*6A variant and colorectal cancer risk.Semantic proximity Read ↗

Colorectal cancers in patients with the (9A/6A) polymorphism of TGFBR1 exhibit lesser inter-(simple sequence repeat) PCR genomic instability and present clinically at greater age.Semantic proximity Read ↗

Infrequent detection of germline allele-specific expression of TGFBR1 in lymphoblasts and tissues of colon cancer patients.Semantic proximity Read ↗

The TGFBR1*6A/9A polymorphism is not associated with differential risk of breast cancer.Semantic proximity Read ↗

Allele-specific expression of TGFBR1 in colon cancer patients.Semantic proximity Read ↗

TGFBR1 variants TGFBR1(*)6A and Int7G24A are not associated with an increased familial colorectal cancer risk.Semantic proximity Read ↗

Prognostic implications of BAX and TGFBRII mutations in colon cancers with microsatellite instability.Semantic proximity Read ↗

Is TGFBR1*6A a susceptibility allele for nonsyndromic familial colorectal neoplasia?Semantic proximity Read ↗

The chromosome 9q genes TGFBR1, TSC1, and ZNF189 are rarely mutated in bladder cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.