Article
Transforming growth factor beta receptor I polyalanine repeat polymorphism does not increase ovarian cancer risk.
Gynecologic oncology - 1 May 2005
Spillman Monique A, Schildkraut Joellen M, Halabi Susan, Moorman Patricia, Calingaert Brian, Bentley Rex C, Marks Jeffrey R, Murphy Susan, Berchuck Andrew
Abstract excerpt
OBJECTIVES: It has been suggested that the 6A allele of the type I TGFbeta receptor (TGFbetaR1) polyalanine repeat tract polymorphism may increase susceptibility to various types of cancer including ovarian cancer. METHODS: The TGFbetaR1 polyalanine polymorphism was genotyped in 588 ovarian cancer cases and 614 controls from a population-based case-control study in North Carolina. RESULTS: Significant racial...
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