Article
Is TGFBR1*6A a susceptibility allele for nonsyndromic familial colorectal neoplasia?
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2007
Daley Denise, Morgan Wendi, Lewis Susan, Willis Joseph, Elston Robert C, Markowitz Sanford D, Wiesner Georgia L
Abstract excerpt
Our analysis definitely excludes the possibility of the TGFBR1*6A allele increasing the risk of colorectal neoplasia in our sample population. A recent study validating linkage of colorectal cancer to chromosome 9q also excluded the TGFBR1*6A allele as a disease-causing variant in that sample. We conclude that there remains an unidentified susceptibility locus in the region 9q22.2-31.2.
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