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Article

Investigation of genotype-dependent differences in factor V activity as well as response to activated protein C by application of different methods.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Dec 2001

Siegert G, Kostka H, Kuhlisch E, Schwarz T, Schellong S M, Jaross W

Abstract excerpt

Coagulation factor V has been at the centre of investigation for several years. In addition to factor V Leiden, various other polymorphisms are becoming the object of interest. Different results have been published about the association of the HR2 haplotype with decreased factor V levels and with reduced response to activated protein C (APC). Due to the central position of factor V in the clotting process, its...

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PMID: 11734669
DOI: 10.1097/00001721-200112000-00010

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Investigation of genotype-dependent differences in factor V activity as well as response to activated protein C by application of different methods.PMID 11734669Read ↗

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