Article
Computation of the full likelihood function for estimating variance at a quantitative trait locus.
Genetics - 1 Dec 1996
Xu S
Abstract excerpt
The proportion of alleles identical by descent (IBD) determines the genetic covariance between relatives, and thus is crucial in estimating genetic variances of quantitative trait loci (QTL). However, IBD proportions at QTL are unobservable and must be inferred from marker information. The conventional method of QTL variance analysis maximizes the likelihood function by replacing the missing IBDs by their...
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